Environmental Confounding in Gene-Environment Interaction Studies
نویسندگان
چکیده
منابع مشابه
Practice of Epidemiology Environmental Confounding in Gene-Environment Interaction Studies
We show that, in the presence of uncontrolled environmental confounding, joint tests for the presence of a main genetic effect and gene-environment interaction will be biased if the genetic and environmental factors are correlated, even if there is no effect of either the genetic factor or the environmental factor on the disease. When environmental confounding is ignored, such tests will in fac...
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ژورنال
عنوان ژورنال: American Journal of Epidemiology
سال: 2013
ISSN: 0002-9262,1476-6256
DOI: 10.1093/aje/kws439